Tumor Extracellular Matrix Remodeling: New Perspectives as a Circulating Tool in the Diagnosis and Prognosis of Solid Tumors.
Giussani M, Triulzi T, Sozzi G, Tagliabue E
J Cells. 2019 Jan 23;8(2). pii: E81. doi: 10.3390/cells8020081. Review.

2019

Immunosuppressive circuits in tumor microenvironment and their influence on cancer treatment efficacy.
Tuccitto A, Shahaj E, Vergani E, Ferro S, Huber V, Rodolfo M, Castelli C, Rivoltini L, Vallacchi V.
Virchows Arch. 2018 Oct 29. doi: 10.1007/s00428-018-2477-z

2018

A novel computational method for automatic segmentation, quantification and comparative analysis of immunohistochemically labeled tissue sections
Casiraghi E, Huber V, Frasca M, Cossa M, Tozzi M, Rivoltini L, Leone BE, Villa A and Vergani B.
BMC Bioinformatics 2018 Oct 15;19(Suppl 10):357. doi: 10.1186/s12859-018-2302-3.

2018

p53 mutants cooperate with HIF-1 in transcriptional regulation of extracellular matrix components to promote tumor progression.
Amelio I, Mancini M, Petrova V, Cairns RA, Vikhreva P, Nicolai S, Marini A, Antonov AA, Le Quesne J, Baena Acevedo JD, Dudek K, Sozzi G, Pastorino U, Knight RA, Mak TW, Melino G.
Proc Natl Acad Sci U S A.
2018 Oct 31. pii: 201808314.
doi: 10.1073/pnas.1808314115

2018

Effect of Tobacco Smoking Cessation on C-Reactive Protein Levels in A Cohort of Low-Dose Computed Tomography Screening Participants.
Gallus S, Lugo A, Suatoni P, Taverna F, Bertocchi E, Boffi R, Marchiano A, Morelli D,
Pastorino U.
Sci Rep. 2018 Aug 27;
8(1):12908. doi: 10.1038/s41598-018-29867-9.

2018

Tumor-derived microRNAs induce myeloid suppressor cells and predict immunotherapy resistance in melanoma.
Huber V, Vallacchi V, Fleming V, Hu X, Cova A, Dugo M, Shahaj E, Sulsenti R, Vergani E, Filipazzi P, De Laurentiis A, Lalli L, Di Guardo L, Patuzzo R, Vergani B, Casiraghi E, Cossa M, Gualeni A, Bollati V, Arienti F, De Braud F, Mariani L, Villa A, Altevogt P, Umansky V, Rodolfo M, Rivoltini L.
J Clin Invest. 2018 Sep 27. pii: 98060. doi: 10.1172/JCI98060.

2018

Diagnostic role of circulating extracellular matrix-related proteins in non-small cell lung cancer
Andriani F, Landoni E, Mensah M, Facchinetti F, Miceli R, Tagliabue E, Giussani M, Callari M, De Cecco L, Colombo MP, Roz L, Pastorino U, Sozzi G
BMC Cancer. 2018
Sep 18;18(1):899.
doi: 10.1186/s12885-018-4772-0.

2018

Mechanisms of tumor immunotherapy, with a focus on thoracic cancers
Ferro S, Huber V, Rivoltini L
J Thorac Dis. 2018
Jul;10(7):4619-4631.
doi: 10.21037/jtd.2018.07.30.

2018

MiR-16 regulates the pro-tumorigenic potential of lung fibroblasts through the inhibition of HGF production in an FGFR-1 and MEK1-dependent manner
Andriani F, Majorini MT, Mano M, Landoni E, Miceli R, Facchinetti F, Mensah M, Fontanella E, Dugo M, Giacca M, Pastorino U, Sozzi G, Delia D, Roz L, Lecis D
Journal of Hematology &
Oncology (2018) 11:45

2018

Extracellular matrix proteins as diagnostic markers of breast carcinoma.
Giussani M, Landoni E, Merlino G, Turdo F, Veneroni S, Paolini B, Cappelletti V, Miceli R, Orlandi R, Triulzi T, Tagliabue E.
J Cell Physiol. 2018 Mar 9.
doi: 10.1002/jcp.26513.

2018

Towards automatic pulmonary nodule management in lung cancer screening with deep learning.
Ciompi F, Chung K, van Riel SJ, Setio AAA, Gerke PK, Jacobs C, Scholten ET, Schaefer-Prokop C, Wille MMW, Marchianò A, Pastorino U, Prokop M,
van Ginneken B.
Sci Rep. 2017 Apr 19;7:46479.
doi: 10.1038/srep46479.
Erratum in: Sci Rep. 2017 Sep 07;7:46878.

2017

Eleven-year management of prostate cancer patients on active surveillance: what have we learned?
Marenghi C, Alvisi MF, Palorini F, Avuzzi B, Badenchini F, Bedini N, Bellardita L, Biasoni D, Bosetti D, Casale A, Catanzaro M, Colecchia M, De Luca L, Donegani S, Dordoni P, Lanocita R, Maffezzini M, Magnani T, Menichetti J, Messina A, Morlino S, Paolini B, Rancati T, Stagni S, Tesone A, Torelli T, Tulli Baldoin E, Vaiani M, Villa S, Villa S, Zaffaroni N, Nicolai N, Salvioni R, Valdagni R. Tumori. 2017 Jun 14:0.
doi: 10.5301/tj.5000649

2017

Prognostic and functional role of subtype-specific tumor-stroma interaction in breast cancer. Merlino G, Miodini P, Callari M, D'Aiuto F, Cappelletti V,
Daidone MG.
Mol Oncol. 2017 Jul 3.
doi: 10.1002/1878-0261.12107.

2017

Persistent immune stimulation exacerbates genetically-driven myeloproliferative disorders via stromal remodeling.
Tripodo C, Burocchi A, Piccaluga PP, Chiodoni C, Portararo P, Cappetti B, Botti L, Gulino A, Isidori A, Liso A, Visani G,
Martelli MP, Falini B, Pandolfi PP, Colombo MP, Sangaletti S
Cancer Res.
2017 Jul 1;77(13):3685-3699.
doi: 10.1158/0008-5472.
CAN-17-1098. Epub 2017 May 23

2017

Baseline and postoperative
C-reactive protein levels predict mortality in operable lung cancer. Pastorino U, Morelli D, Leuzzi G, Gisabella M, Suatoni P, Taverna F, Bertocchi E, Boeri M, Sozzi G, Cantarutti A, Corrao G.
Eur J Cancer. 2017 Jul;79:90-97. doi: 10.1016/j.ejca.2017.03.020. Epub 2017 May 1.

2017

microRNAs as players and signals in the metastatic cascade: Implications for the development of novel anti-metastatic therapies
Gandellini P, Doldi V, Zaffaroni N
Semin Cancer Biol. 2017 Jun;44:132-140. doi: 10.1016/j.semcancer.2017.03.005.
Epub 2017 Mar 23.

2017

Inflammatory status and lung function predict mortality in lung cancer screeing participants
Pastorino U, Morelli D, Marchianò A, Sestini S, Suatoni P, taverna F, Boeri M, Sozzi G, Cantarutti A and Corrao G
Eur J Cancer Prev. 2017 Mar 23.
doi: 10.1097/
CEJ.0000000000000342.

2017

Mutational Profile from Targeted NGS Predicts Survival in LDCT Screening-Detected Lung Cancers
Verri C, Borzi C, Holscher T, Dugo M, Devecchi A, Drake K, Sestini S, Suatoni P, Romeo E, Sozzi G, Pastorino U, Boeri M
J Thorac Oncol. 2017 Jun;12(6):922-931. doi: 10.1016/j.jtho.2017.03.001.
Epub 2017 Mar 14.

2017

A methodological procedure for evaluating the impact of hemolysis on circulating microRNAs
Pizzamiglio S, Zanutto S, Ciniselli CM, Belfiore A, Bottelli S, Gariboldi M and Verderio P
Oncol Lett. 2017 Jan;13(1):315-320. doi: 10.3892/ol.2016.5452. Epub 2016 Nov 30.

2017

miR-875-5p counteracts epithelial-to-mesenchymal transition and enhances radiation response in prostate cancer through repression of the EGFR-ZEB1 axis
El Bezawy R, Cominetti D, Fenderico N, Zuco V, Beretta GL, Dugo M, Arrighetti N, Stucchi C, Rancati T, Valdagni R, Zaffaroni N, Gandellini P
Cancer Lett. 2017 Jun 1;395:53-62. doi: 10.1016/j.canlet.2017.02.033. Epub 2017 Mar 6.

2017

mir-660-p53-mir-486 Network: A New Key Regulatory Pathway in Lung Tumorigenesis.
Borzi C, Calzolari L, Centonze G, Milione M, Sozzi G, Fortunato O.
Int J Mol Sci. 2017 Jan 23;18(1). pii: E222. doi: 10.3390/ijms18010222.

2017

Metabolic Evaluation of Non-Small Cell Lung Cancer Patient-Derived Xenograft Models Using 18F-FDG PET: A Potential Tool for Early Therapy Response.
Valtorta S, Moro M, Prisinzano G, Bertolini G, Tortoreto M, Raccagni I, Pastorino U, Roz L, Sozzi G, Moresco RM.
J Nucl Med. 2017 Jan;58(1):42-47. doi: 10.2967/jnumed.116.176404. Epub 2016 Oct 20.

2017

Breast cancer-secreted miR-939 downregulates VE-cadherin and destroys the barrier function of endothelial monolayers.
Di Modica M, Regondi V, Sandri M, Iorio MV, Zanetti A, Tagliabue E, Casalini P, Triulzi T.
Cancer Lett. 2017 Jan 1;384:94-100. doi: 10.1016/j.canlet.2016.09.013.
Epub 2016 Sep 28.

2017

Lung cancer screening with low-dose spiral computed tomography: evidence from a pooled analysis of two Italian randomized trials.
Infante M, Sestini , Galeone C, Marchianò A, Lutman FR, Angeli E, Calareso G, Pelosi G, Sozzi G, Silva M, Sverzellati N, Cavuto S,
La Vecchia C, Santoro A, Alloisio M, Pastorino U.
Eur J Cancer Prev.
2017 Jul;26(4):324-329.
doi: 10.1097/
CEJ.0000000000000264.

2017

C1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation.
Bulla R, Tripodo C, Rami D, Ling GS, Agostinis C, Guarnotta C, Zorzet S, Durigutto P, Botto M, Tedesco F.
Nat Commun. 2016 Feb 1;7:10346. doi: 10.1038/ncomms10346.

2016

Heterotypic paracrine signaling drives fibroblast senescence and tumor progression of large cell carcinoma of the lung.
Lugo R, Gabasa M, Andriani F, Puig M, Facchinetti F, Ramírez J, Gómez-Caro A, Pastorino U, Fuster G, Almendros I, Gascón P, Davalos A, Reguart N, Roz L, Alcaraz J.
Oncotarget. 2016 Dec 13;7(50):82324-82337. doi: 10.18632/oncotarget.10327.

2016

Parametric and nonparametric two-sample tests for feature screening in class comparison: a simulation study
Landoni E, Ambrogi F, Mariani L, Miceli R.
Epidemiology Biostatistics and Public Health - 2016, Volume 13, Number 2. e11808-1-11. doi: 10.2427/11808

2016

Stromal Activation by Tumor Cells: An in Vitro Study in Breast Cancer.
Merlino G, Miodini P, Paolini B, Carcangiu ML, Gennaro M, Dugo M, Daidone MG, Cappelletti V.
Microarrays (Basel). 2016 May 18;5(2). pii: E10. doi: 10.3390/microarrays5020010.

2016

MicroRNA Profile of Lung Tumor Tissues Is Associated with a High Risk Plasma miRNA Signature.
Fortunato O, Verri C, Pastorino U, Sozzi G, Boeri M.
Microarrays (Basel). 2016 Jul 5;5(3). pii: E18. doi: 10.3390/microarrays5030018.

2016

Mesenchymal Transition of High-Grade Breast Carcinomas Depends on Extracellular Matrix Control of Myeloid Suppressor Cell Activity.
Sangaletti S, Tripodo C, Santangelo A, Castioni N, Portararo P, Gulino A, Botti L, Parenza M, Cappetti B, Orlandi R, Tagliabue E, Chiodoni C, Colombo MP.
Cell Rep. 2016 Sep 27;17(1):233-48. doi: 10.1016/j.celrep.2016.08.075.

2016

Comment on 'Circulating cell-free miRNAs as biomarker for triple-negative breast cancer'-Methodological challenges in combining miRNAs as circulating biomarkers.
Verderio P, Bottelli S, Lecchi M, Plebani M, Gariboldi M, Pizzamiglio S, Ciniselli CM.
Br J Cancer.
2016 May 10;114(10):e5.
doi: 10.1038/bjc.2016.1.
Epub 2016 Apr 21.

2016

Developing miRNAs signatures: a multivariate prospective
Verderio P, Bottelli S, Pizzamiglio S, and Ciniselli C
Br J Cancer. 2016 Jun 28;115(1):1-4. doi: 10.1038/bjc.2016.164.

2016

MicroRNAs and the Response of Prostate Cancer to Anti-Cancer Drugs.
Pennati M, Folini M, Gandellini P, Zaffaroni N.
Curr Drug Targets. 2016;17(3):257-65. Review.

2016

A subset of genetic susceptibility variants for colorectal cancer also has prognostic value
Noci S, Dugo M, Bertola F, Melotti F, Vannelli A, Dragani TA and  Galvan A
Pharmacogenomics J.
2016 Apr;16(2):173-9.
doi: 10.1038/tpj.2015.35.
Epub 2015 May 12.

2016

Stopping Smoking Reduces Mortality in Low-Dose Computed Tomography Screening Participants
Pastorino U, Boffi R, Marchianò A, Sestini S, Munarini E, Calareso G, Boeri M, Pelosi G, Sozzi G, Silva M, Sverzellati N, Galeone C, La Vecchia C, Ghirardi A, Corrao G
J Thorac Oncol. 2016 May;11(5):693-9. doi: 10.1016/j.jtho.2016.02.011.
Epub 2016 Feb 24.

2016

Low-dose computed tomography for lung cancer screening: comparison of performance between annual and biennial screen.
Sverzellati N, Silva M, Calareso G, Galeone C, Marchianò A, Sestini S, Sozzi G, Pastorino U.
Eur Radiol. 2016 Nov;26(11):3821-3829.
Epub 2016 Feb 11. doi: 10.1007/s00330-016-4228-3

2016

microRNA Expression in Sentinel Nodes from Progressing Melanoma Patients Identifies Networks Associated with Dysfunctional Immune Response.
Vallacchi V, Camisaschi C, Dugo M, Vergani E, Deho P, Gualeni A, Huber V, Gloghini A, Maurichi A, Santinami M, Sensi M, Castelli C, Rivoltini L, Rodolfo M.
Genes (Basel). 2016 Dec 14;7(12). pii: E124.

2016

Dissecting the role of microRNAs in prostate cancer metastasis: implications for the design of novel therapeutic approaches. 
Doldi V, Pennati M, Forte B, Gandellini P, Zaffaroni N
Cell Mol Life Sci. 2016 Jul;73(13):2531-42. doi: 10.1007/s00018-016-2176-3. Epub 2016 Mar 12.

2016

Integration of genome scale data for identifying new players in colorectal cancer. 
Sokolova V, Crippa E,
Gariboldi M. 
World J Gastroenterol.
2016 Jan 14;22(2):534-45.
doi: 10.3748/wjg.v22.i2.534.

2016

Screening with Low-Dose Computed Tomography Does Not Improve Survival of Small Cell Lung Cancer.
Silva M, Galeone C, Sverzellati N, Marchianò A, Calareso G, Sestini S, La Vecchia C, Sozzi G, Pelosi G, Pastorino U.
J Thorac Oncol. 2016 Feb;11(2):187-93. doi: 10.1016/j.jtho.2015.10.014.
Epub 2015 Dec 23.

2016

Conversion to stem-cell state in response to microenvironmental cues is regulated by balance between epithelial and mesenchymal features in lung cancer cells.
Andriani F, Bertolini G, Facchinetti F, Baldoli E, Moro M, Casalini P, Caserini R, Milione M, Leone G, Pelosi G, Pastorino U, Sozzi G,
Roz L.
Mol Oncol. 2016 Feb;10(2):253-71. doi: 10.1016/j.molonc.2015.10.002.
Epub 2015 Oct 22.

2016

Read-through transcripts in normal human lung parenchyma are down-regulated in lung adenocarcinoma.
Pintarelli G, Dassano A, Cotroneo CE, Galvan A, Noci S, Piazza R, Pirola A, Spinelli R, Incarbone M, Palleschi A, Rosso L, Santambrogio L, Dragani TA, Colombo F.
Oncotarget. 2016 May 10;7(19):27889-98. doi: 10.18632/oncotarget.8556.

2016

Overcoming melanoma resistance to vemurafenib by targeting CCL2-induced miR-34a, miR-100 and miR-125b.
Vergani E, Di Guardo L, Dugo M, Rigoletto S, Tragni G, Ruggeri R, Perrone F, Tamborini E, Gloghini A, Arienti F, Vergani B, Deho D, De Cecco L, Vallacchi V, Frati P, Shahaj E, Villa A, Santinami M, De Braud F, Rivoltini L, Rodolfo M.
Oncotarget. 2016 Jan 26;7(4):4428-41. doi: 10.18632/oncotarget.6599.

2016

RORC1 Regulates Tumor-Promoting "Emergency" Granulo-Monocytopoiesis.
Strauss L, Sangaletti S, Consonni FM, Szebeni G, Morlacchi S, Totaro MG, Porta C, Anselmo A, Tartari S, Doni A, Zitelli F, Tripodo C, Colombo MP, Sica A.
Cancer Cell. 2015 Aug 10;28(2):253-69. doi: 10.1016/j.ccell.2015.07.006.

2015

miR-30e* is an independent subtype-specific prognostic marker in breast cancer.
D'Aiuto F, Callari M, Dugo M, Merlino G, Musella V, Miodini P, Paolini B, Cappelletti V,
Daidone MG.
Br J Cancer.
2015 Jul 14;113(2):290-8.
doi: 10.1038/bjc.2015.206.
Epub 2015 Jun 9.

2015

Novel method to detect microRNAs using chip-based QuantStudio 3D digital PCR.
Conte D, Verri C, Borzi C, Suatoni P, Pastorino U, Sozzi G,
Fortunato O.
BMC Genomics. 2015 Oct 23;16:849. doi: 10.1186/s12864-015-2097-9.

2015

Circulating Biomarkers for Prediction of Treatment Response.
Cappelletti V, Appierto V, Tiberio P, Fina E, Callari M, Daidone MG.
J Natl Cancer Inst Monogr. 2015 May;2015(51):60-3. doi: 10.1093/jncimonographs/lgv006.

2015

By promoting cell differentiation, miR-100 sensitizes basal-like breast cancer stem cells to hormonal therapy
Petrelli A, Carollo R, Cargnelutti M, Iovino F, Callari M, Cimino D, Todaro M, Mangiapane LR, Giammona A, Cordova A, Montemurro F, Taverna D, Daidone MG, Stassi G, Giordano S.
Oncotarget. 2015 Feb 10;6(4):2315-30.

2015

Gene expression profiling of circulating tumor cells in breast cancer.
Fina E, Callari M, Reduzzi C, D'Aiuto F, Mariani G, Generali D, Pierotti MA, Daidone MG, Cappelletti V.
Clin Chem. 2015 Jan;61(1):278-89. doi: 10.1373/clinchem.2014.229476.
Epub 2014 Nov 19.

2015

Targeting microRNAs to withstand cancer metastasis.
Profumo V, Doldi V, Gandellini P, Zaffaroni N.
Methods Mol Biol. 2015;1218:415-37. doi: 10.1007/978-1-4939-1538-5_25.

2015

Proposal of supervised data analysis strategy of plasma miRNAs from hybridisation array data with an application to assess hemolysis-related deregulation.
Landoni E, Miceli R, Callari M, Tiberio P, Appierto V, Angeloni V, Mariani L, Daidone MG.
BMC Bioinformatics. 2015 Nov 18;16:388. doi: 10.1186/s12859-015-0820-9.

2015

Integrated gene and miRNA expression analysis of prostate cancer associated fibroblasts supports a prominent role for interleukin-6 in fibroblast activation.
Doldi V, Callari M, Giannoni E, D'Aiuto F, Maffezzini M, Valdagni R, Chiarugi P, Gandellini P, Zaffaroni N
Oncotarget. 2015 Oct 13;6(31):31441-60. doi: 10.18632/oncotarget.5056.

2015

Tumor-extracellular matrix interactions: Identification of tools associated with breast cancer progression.
Giussani M, Merlino G, Cappelletti V, Tagliabue E, Daidone MG
Semin Cancer Biol. 2015 Dec;35:3-10. doi: 10.1016/j.semcancer.2015.09.012. Epub 2015 Sep 28.

2015

Complexity in the tumour microenvironment: Cancer associated fibroblast gene expression patterns identify both common and unique features of tumour-stroma crosstalk across cancer types.
Gandellini P, Andriani F, Merlino G, D'Aiuto F, Roz L, Callari M
Semin Cancer Biol. 2015 Dec;35:96-106. doi: 10.1016/j.semcancer.2015.08.008.
Epub 2015 Aug 28

2015

Germline polymorphisms and survival of lung adenocarcinoma patients: A genome-wide study in two European patient series.
Galvan A, Colombo F, Frullanti E, Dassano A, Noci S, Wang Y, Eisen T, Matakidou A, Tomasello L, Vezzalini M, Sorio C, Dugo M, Ambrogi F, Iacobucci I, Martinelli G, Incarbone M, Alloisio M, Nosotti M, Tosi D, Santambrogio L, Pelosi G, Pastorino U, Houlston RS, Dragani TA
Int J Cancer.
2015 Mar 1;136(5):E262-71.
doi: 10.1002/ijc.29195.
Epub 2014 Sep 19

2015

The Effects of miR-20a on p21: Two Mechanisms Blocking Growth Arrest in TGF-ß Responsive Colon Carcinoma.
Sokolova V, Fiorino A, Zoni E, Crippa E, Reid JF, Gariboldi M, Pierotti MA
J Cell Physiol. 2015 Dec;230(12):3105-14. doi: 10.1002/jcp.25051

2015

Moving from discovery to validation in circulating microRNA research.
Verderio P, Bottelli S, Ciniselli CM, Pierotti MA, Zanutto S, Gariboldi M, Pizzamiglio S
Int J Biol Markers. 2015 May 26;30(2):e258-61. doi: 10.5301/jbm.5000135.

2015

SOCS2 Controls Proliferation and Stemness of Hematopoietic Cells under Stress Conditions and Its Deregulation Marks Unfavorable Acute Leukemias.
Vitali C, Bassani C, Chiodoni C, Fellini E, Guarnotta C, Miotti S, Sangaletti S, Fuligni F, De Cecco L, Piccaluga PP, Colombo MP, Tripodo C
Cancer Res. 2015 Jun 1;75(11):2387-99. doi: 10.1158/0008-5472.CAN-14-3625. Epub 2015 Apr 9.

2015

Interleukin 21 Controls mRNA and MicroRNA Expression in CD40-Activated Chronic Lymphocytic Leukemia Cells.
De Cecco L, Capaia M, Zupo S, Cutrona G, Matis S, Brizzolara A, Orengo AM, Croce M, Marchesi E, Ferrarini M, Canevari S, Ferrini S
PLoS One. 2015 Aug 25;10(8):e0134706. doi: 10.1371/journal.pone.0134706.
eCollection 2015.

2015

Recent advances of microRNA-based molecular diagnostics to reduce false-positive lung cancer imaging.
Boeri M, Sestini S, Fortunato O, Verri C, Suatoni P, Pastorino U, Sozzi G
Expert Rev Mol Diagn. 2015 Jun;15(6):801-13. doi: 10.1586/14737159.2015.1041377. Epub 2015 Apr 30.

2015

Microenvironment modulated
metastatic CD133+/CXCR4+/
EpCAM- lung cancer initiating
cells sustain tumor dissemination
and correlate with poor prognosis.
Bertolini G, D'Amico L, Moro M, Landoni E, Perego P, Miceli R, Gatti L, Andriani F, Wong D, Caserini R, Tortoreto M,
Milione M, Ferracini R,
Mariani L, Pastorino U, Roato I, Sozzi G, Roz L
Cancer Res. 2015 Sep 1;75(17):3636-49. doi: 10.1158/0008-5472.CAN-14-3781. Epub 2015 Jul 3.

2015

Gene Signatures Stratify Computed Tomography Screening Detected Lung Cancer in High-Risk Populations.
Hu J, Boeri M, Sozzi G, Liu D, Marchianò A, Roz L, Pelosi G, Gatter K, Pastorino U, Pezzella F
EBioMedicine. 2015 Jul 8;2(8):831-40. doi: 10.1016/j.ebiom.2015.07.001. eCollection 2015 Aug.

2015

Circulating microRNA signature as liquid-biopsy to monitor lung cancer in low-dose computed tomography screening.
Sestini S, Boeri M, Marchiano A, Pelosi G, Galeone C, Verri C, Suatoni P, Sverzellati N, La Vecchia C, Sozzi G, Pastorino U
Oncotarget. 2015 Oct 20;6(32):32868-77. doi: 10.18632/oncotarget.5210.

2015

Oligogenic germline mutations identified in early non-smokers lung adenocarcinoma patients.
Renieri A, Mencarelli MA, Cetta F, Baldassarri M, Mari F, Furini S, Piu P, Ariani F, Dragani TA, Frullanti E.
Lung Cancer. 2014 Aug;85(2):168-74. doi: 10.1016/j.lungcan.2014.05.020.
Epub 2014 Jun 4.

2014

Assessment of circulating microRNAs in plasma of lung cancer patients.
Fortunato O, Boeri M, Verri C, Conte D, Mensah M, Suatoni P, Pastorino U, Sozzi G
Molecules. 2014 Mar 10;19(3):3038-54. doi: 10.3390/molecules19033038.

2014

Senescent stroma promotes prostate cancer progression: The role of miR-210.
Taddei ML, Cavallini L, Comito G, Giannoni E, Folini M, Marini A, Gandellini P, Morandi A, Pintus G, Raspollini MR, Zaffaroni N, Chiarugi P
Mol Oncol. 2014 Dec;8(8):1729-46. doi: 10.1016/j.molonc.2014.07.009.
Epub 2014 Jul 21.

2014

miR-205 impairs the autophagic flux and enhances cisplatin cytotoxicity in castration-resistant prostate cancer cells.
Pennati M, Lopergolo A, Profumo V, De Cesare M, Sbarra S, Valdagni R, Zaffaroni N, Gandellini P,
Folini M
Biochem Pharmacol. 2014 Feb 15;87(4):579-97. doi: 10.1016/j.bcp.2013.12.009.
Epub 2013 Dec 24.

2014

miR-205 hinders the malignant interplay between prostate cancer cells and associated fibroblasts.
Gandellini P, Giannoni E, Casamichele A, Taddei ML, Callari M, Piovan C, Valdagni R, Pierotti MA, Zaffaroni N, Chiarugi P
Antioxid Redox Signal.
2014 Mar 1;20(7):1045-59.
doi: 10.1089/ars.2013.5292.
Epub 2013 Sep 17.

2014

Maspin influences response to doxorubicin by changing the tumor microenvironment organization.
Triulzi T, Ratti M, Tortoreto M, Ghirelli C, Aiello P, Regondi V, Modica MD, Cominetti D, Carcangiu ML, Moliterni A, Balsari A, Casalini P, Tagliabue E
Int J Cancer.
2014 Jun 15;134(12):2789-97.
doi: 10.1002/ijc.28608.
Epub 2013 Nov 30

2014

Clinical Utility of a Plasma-Based miRNA Signature Classifier Within Computed Tomography Lung Cancer Screening: A Correlative MILD Trial Study.
Sozzi G, Boeri M, Rossi M, Verri C, Suatoni P, Bravi F, Roz L, Conte D, Grassi M, Sverzellati N, Marchiano A, Negri E, La Vecchia C,
Pastorino U
J Clin Oncol. 2014 Mar 10;32(8):768-73. doi: 10.1200/JCO.2013.50.4357.
Epub 2014 Jan 13.

2014

NqA: an R-based algorithm for the normalization and analysis of microRNA quantitative real-time polymerase chain reaction data.
Verderio P, Bottelli S, Ciniselli CM, Pierotti MA, Gariboldi M, Pizzamiglio S
Anal Biochem.
2014 Sep 15;461:7-9.
doi: 10.1016/j.ab.2014.05.020.
Epub 2014 Jun 2.

2014

miR-342 Regulates BRCA1 Expression through Modulation of ID4 in Breast Cancer.
Crippa E, Lusa L, De Cecco L, Marchesi E, Calin GA, Radice P, Manoukian S, Peissel B, Daidone MG, Gariboldi M, Pierotti MA
PLoS One. 2014 Jan 27;9(1):e87039. doi: 10.1371/journal.pone.0087039.
eCollection 2014.

2014

Circulating miR-378 in plasma: a reliable, haemolysis-independent biomarker for colorectal cancer.
Zanutto S, Pizzamiglio S, Ghilotti M, Bertan C, Ravagnani F, Perrone F, Leo E, Pilotti S, Verderio P, Gariboldi M, Pierotti MA
Br J Cancer.
2014 Feb 18;110(4):1001-7.
doi: 10.1038/bjc.2013.819.
Epub 2014 Jan 14.

2014

Circulating free DNA in a screening program for early colorectal cancer detection.
Perrone F, Lampis A, Bertan C, Verderio P, Ciniselli CM, Pizzamiglio S, Frattini M, Nucifora M, Molinari F, Gallino G, Gariboldi M, Meroni E, Leo E, Pierotti MA, Pilotti S
Tumori.
2014 Mar-Apr;100(2):115-21.
doi: 10.1700/1491.16389.

2014

A normalization strategy for the analysis of plasma microRNA qPCR data in colorectal cancer.
Pizzamiglio S, Bottelli S, Ciniselli CM, Zanutto S, Bertan C, Gariboldi M, Pierotti MA, Verderio P
Int J Cancer.
2014 Apr 15;134(8):2016-8.
doi: 10.1002/ijc.28530.
Epub 2013 Oct 22.

2014

Stromal niche communalities underscore the contribution of the matricellular protein SPARC to B-cell development and lymphoid malignancies.
Sangaletti S, Tripodo C, Portararo P, Dugo M, Vitali C, Botti L, Guarnotta C, Cappetti B, Gulino A, Torselli I, Casalini P, Chiodoni C, Colombo MP
Oncoimmunology. 2014 Jun 5;3:e28989. eCollection 2014.

2014

Defective stromal remodeling and neutrophil extracellular traps in lymphoid tissues favor the transition from autoimmunity to lymphoma.
Sangaletti S, Tripodo C, Vitali C, Portararo P, Guarnotta C, Casalini P, Cappetti B, Miotti S, Pinciroli P, Fuligni F, Fais F, Piccaluga PP, Colombo MP
Cancer Discov. 2014 Jan;4(1):
110-29. doi: 10.1158/2159-8290.
CD-13-0276. Epub 2013 Nov 4.

2014

Bone marrow stroma CD40 expression correlates with inflammatory mast cell infiltration and disease progression in splenic marginal zone lymphoma.
Franco G, Guarnotta C, Frossi B, Piccaluga PP, Boveri E, Gulino A, Fuligni F, Rigoni A, Porcasi R, Buffa S, Betto E, Florena AM, Franco V, Iannitto E, Arcaini L, Pileri SA, Pucillo C, Colombo MP, Sangaletti S, Tripodo C
Blood. 2014 Mar 20;123(12):1836-49. doi: 10.1182/
blood-2013-04-497271.
Epub 2014 Jan 22.

2014

Therapeutic Use of MicroRNAs in Lung Cancer.
Fortunato O, Boeri M, Verri C, Moro M, Sozzi G
Biomed Res Int. 2014;2014:756975. doi: 10.1155/2014/756975.
Epub 2014 Sep 16

2014

Potential biomarkers for lung cancer screening.
Sozzi G, Boeri M
Transl Lung Cancer Res.
2014 Jun;3(3):139-48.
doi: 10.3978/j.issn.2218-
6751.2014.06.04.

2014

Mir-660 is downregulated in lung cancer patients and its replacement inhibits lung tumorigenesis by targeting MDM2-p53 interaction.
Fortunato O, Boeri M, Moro M, Verri C, Mensah M, Conte D, Caleca L, Roz L, Pastorino U,
Sozzi G
Cell Death Dis.
2014 Dec 11;5:e1564.
doi: 10.1038/cddis.2014.507.

2014

Subtype-dependent prognostic relevance of an interferon-induced pathway metagene in node-negative breast cancer.
Callari M, Musella V, Di Buduo E, Sensi M, Miodini P, Dugo M, Orlandi R, Agresti R, Paolini B, Carcangiu ML, Cappelletti V, Daidone MG. 
Mol Oncol. 2014 Oct;8(7):1278-89.
doi: 10.1016/
j.molonc.2014.04.010.
Epub 2014 May 4.

2014

A lipemia-independent NanoDrop(®)-based score to identify hemolysis in plasma and serum samples.
Appierto V, Callari M, Cavadini E, Morelli D, Daidone MG, Tiberio P.
Bioanalysis.
2014 May;6(9):1215-26.
doi: 10.4155/bio.13.344.

2014

Gene expression signature of non-involved lung tissue associated with survival in lung adenocarcinoma patients. 
Galvan A, Frullanti E, Anderlini M, Manenti G, Noci S, Dugo M, Ambrogi F, De Cecco L, Spinelli R, Piazza R, Pirola A, Gambacorti-Passerini C, Incarbone M, Alloisio M, Tosi D, Nosotti M, Santambrogio L, Pastorino U, Dragani TA. 
Carcinogenesis.
2013 Dec;34(12):2767-73.
doi: 10.1093/carcin/bgt294.
Epub 2013 Aug 25

2013

Measuring microRNA expression levels in oncology: from samples to data analysis. 
De Cecco L, Dugo M, Canevari S, Daidone MG, Callari M. 
Crit Rev Oncog.
2013;18(4):273-87.

2013

Feasibility of circulating miRNA microarray analysis from archival plasma samples. 
Callari M, Tiberio P, De Cecco L, Cavadini E, Dugo M, Ghimenti C, Daidone MG, Canevari S,
Appierto V. 
Anal Biochem.
2013 Jun 15;437(2):123-5.
doi: 10.1016/j.ab.2013.03.002.
Epub 2013 Mar 13.

2013

Multiple isoforms and differential allelic expression of CHRNA5 in lung tissue and lung adenocarcinoma. 
Falvella FS, Alberio T, Noci S, Santambrogio L, Nosotti M, Incarbone M, Pastorino U,
Fasano M, Dragani TA. 
Carcinogenesis.
2013 Jun;34(6):1281-5.
doi: 10.1093/carcin/bgt062.
Epub 2013 Feb 19.

2013

Adipose tissue displays trophic properties on normal lung cellular components without promoting cancer cells growth.
Andriani F, Facchinetti F, Furia S, Roz L, Bursomanno S, Bertolini G, Carniti C, Sozzi G, Pastorino U.
J Cell Physiol.
2013 Jun;228(6):1166-73.
doi: 10.1002/jcp.24270.

2013

Neoplastic and stromal cells contribute to an extracellular matrix gene expression profile defining a breast cancer subtype likely to progress.
Triulzi T, Casalini P, Sandri M, Ratti M, Carcangiu ML, Colombo MP, Balsari A, Ménard S, Orlandi R, Tagliabue E. 
PLoS One. 2013;8(2):e56761. doi: 10.1371/journal.pone.0056761. Epub 2013 Feb 18.

2013

MicroRNA-mediated control of prostate cancer metastasis: implications for the identification of novel biomarkers and therapeutic targets.
Fenderico N, Casamichele A, Profumo V, Zaffaroni N,
Gandellini P.  
Curr Med Chem. 2013;20(12):1566-84.

2013

Stromal SPARC contributes to the detrimental fibrotic changes associated with myeloproliferation whereas its deficiency favors myeloid cell expansion. 
Tripodo C, Sangaletti S, Guarnotta C, Piccaluga PP, Cacciatore M, Giuliano M, Franco G, Chiodoni C, Sciandra M, Miotti S, Calvaruso G, Carè A, Florena AM, Scotlandi K, Orazi A, Pileri SA, Colombo MP.
Blood.
2012 Oct 25;120(17):3541-54.
doi: 10.1182/
blood-2011-12-398537.
Epub 2012 Sep 5.

2012

Comparison of microarray platforms for measuring differential microRNA expression in paired normal/cancer colon tissues. 
Callari M, Dugo M, Musella V, Marchesi E, Chiorino G, Grand MM, Pierotti MA, Daidone MG, Canevari S, De Cecco L. 
PLoS One. 2012;7(9):e45105. doi: 10.1371/journal.pone.0045105. Epub 2012 Sep 13

2012

Role of microRNAs in lung cancer: microRNA signatures in cancer prognosis. 
Boeri M, Pastorino U, Sozzi G.
Cancer J.
2012 May-Jun;18(3):268-74.
doi: 10.1097/
PPO.0b013e318258b743

2012